After updating to 378.51 from 376.49_5 and resetting to factory defaults, I'm now having some major issues with my RT-N66U. After resetting to factory defaults and reconfiguring everything, within minutes, I could no longer access external addresses by hostname or the router configuration page. Another factory reset and reconfigure. A day later, the same issue. It suddenly stopped responding to requests. I ran some tests. It pings external addresses, so I know it is connected. However, DNS does not resolve. Additionally, I cannot access the configuration page when this occurs. Error I get is "connection closed" in chrome and "connection interrupted" in Firefox. A reboot does not fix the issue. Only a factory reset and reconfigure will work. I've searched the threads but not seen anything else regarding this issue.
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