I am running AXE16000 + 3x XT12s and previously AX11000 + 3x XT8s. Also had ET12s. For max range for wireless aimesh, then its using 5Ghz band 1 and band2. Typically, 5-band2 is used for backhaul. If your using ET12s, then these routers only support 2.4Ghz, 5Ghz band 1 and 6Ghz (also called WIFI 6e). WIFI 6e is the same speed as 5Ghz-band2 but has really low range. ET12 routers are great for wired backhaul. I bought ET12s, tested them out on wireless aimesh & then returned them as the wireless aimesh performance + range is severely lacking for my use. Also bear in mind, the amount of bandwidth you need. You can do aimmesh router > wifi node1>wifi node2 which will increase the range but will lowers the overall speed you get on node2.
If it was myself I had ET12s and wanted to expand the setup for bigger coverage, then I'd expand using ET12 but only via wired aimesh nodes. As for AXE16k, it had 2.4Ghz/5Ghz-band1/5Ghz-band2/6Ghz and also supports 160mhz bands on 5-1/5-2/6Ghz bands, hopefully AXE16k gets UNII4 support so wireless mesh speeds get even better. My advice is that its your money. Learn what radios each router you have has, how the mesh works if your using wireless, then see how it fits. At the moment, AX routers are best for range, remember - ET12s in wired backhaul will give you 2.5Gbps backhaul bandwidth & full speed 5ghz + 6Ghz from the ET12 (ET12 to ET12).