the main difference is, the guest network is a different subnet from the main network, so it isolates the bulbs from the main network traffic, and vs versa . One thing I can also report is, a couple of my Echo devices, would always report a busy wifi network with everything on one network, now that the bulbs are on their own supbnet and their traffic isn't on the main network, the same Echo devices that used to report noisy / busy wireless, report everything is clean.
So, the take away here is, putting the bulbs on their own subnet solved the problem. This just happened to be way of a guest network in this case. One additional thought to add here, I could have probably solved the same problem with a double NAT using two routers.