Most models (if not all, I don't remember specifically) should be able to use Asus' bypass method that will leave hardware acceleration enabled for regular WAN traffic, only traffic going through the tunnel will be marked to bypass acceleration.Good news! Thanks!
BTW: Does this note still apply?Note that enabling WireGuard will disable hardware NAT acceleration due to compatibility reasons.
Look at the content of the changelog, it was documented at the time, whether some models were excluded from this implementation.