You're being much too aggressive with your settings.
Use a wired computer with 1Gbps LAN to adjust your settings. Using a wireless device is an exercise in futility when trying to set up QoS.
Start at the settings you're paying your ISP. In your case, 100 down and 45 up (make sure you are not switching these values in the GUI).
Decrease the download speed by 5Mbps at a time, making sure to test and simply browse the 'net for at least a few minutes in between before taking good notes and changing the download speeds once again by 5Mbps. You will quickly see where the best values are by referencing your notes. Now, do the same for upload speeds. Finally, you may want to fine-tune these values by getting to the optimum/closest 1Mbps values for your connection. Don't forget, it will be optimum for 'now', whenever that 'now' is that you do this process.
This is something that you may want to revisit/check every few weeks. Yes, things change.
HTH.